Estimation of Maximal Cortisol Secretion Rate in Healthy Humans

CONTEXT: Cortisol secretion is related to ACTH concentration by a sigmoidal dose-response curve, in which high ACTH concentrations drive maximal cortisol secretion rates (CSR(max)). OBJECTIVE: We sought to estimate CSR(max) and free cortisol half-life in healthy humans (n = 21) using numerical metho...

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Bibliografiske detaljer
Main Authors: Dorin, Richard I., Qiao, Zhi, Qualls, Clifford R., Urban, Frank K.
Format: Artigo
Sprog:Inglês
Udgivet: Endocrine Society 2012
Fag:
Endocrine Care
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319177/
https://ncbi.nlm.nih.gov/pubmed/22337905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2011-2227
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