S-ADENOSYLMETHIONINE DECREASES THE PEAK BLOOD ALCOHOL LEVELS 3 HOURS AFTER AN ACUTE BOLUS OF ETHANOL BY INDUCING ALCOHOL METABOLIZING ENZYMES IN THE LIVER

INTRODUCTION: An alcohol bolus causes the blood alcohol level (BAL) to peak at 1-2 hours post ingestion. The ethanol elimination rate is regulated by alcohol metabolizing enzymes, primarily alcohol dehydrogenase (ADH1), acetaldehyde dehydrogenase (ALDH), and cytochrome P450 (CYP2E1). Recently, S-ade...

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Main Authors: Bardag-Gorce, Fawzia, Oliva, Joan, Wong, Wesley, Fong, Stephanie, Li, Jun, French, Barbara A., French, Samuel W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319153/
https://ncbi.nlm.nih.gov/pubmed/20828554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexmp.2010.08.010
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