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5-Nitroindole as an universal base analogue.

4-, 5- and 6-Nitroindole have been investigated and compared with 3-nitropyrrole as universal bases in oligodeoxynucleotides. Of these the 5-nitroindole derivative was found to be superior giving higher duplex stability, and behaving indiscriminately towards each of the four natural bases in duplex...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Loakes, D, Brown, D M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1994
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC331887/
https://ncbi.nlm.nih.gov/pubmed/7937128
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