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In vivo detection of gene expression in liver by (31)P nuclear magnetic resonance spectroscopy employing creatine kinase as a marker gene

In vivo assessment of gene expression is desirable to obtain information on the extent and duration of transduction of tissue after gene delivery. We have developed an in vivo, potentially noninvasive, method for detecting virally mediated gene transfer to the liver. The method employs an adenoviral...

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Autores principales: Auricchio, Alberto, Zhou, Rong, Wilson, James M., Glickson, Jerry D.
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 2001
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC33188/
https://ncbi.nlm.nih.gov/pubmed/11296261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.081508598
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