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Caenorhabditis elegans RNA-processing Protein TDP-1 Regulates Protein Homeostasis and Life Span

Transactive response DNA-binding protein (TARDBP/TDP-43), a heterogeneous nuclear ribonucleoprotein (hnRNP) with diverse activities, is a common denominator in several neurodegenerative disorders, including amyotrophic lateral sclerosis and frontotemporal lobar degeneration. Orthologs of TDP-43 exis...

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Hlavní autoři: Zhang, Tao, Hwang, Ho-Yon, Hao, Haiping, Talbot, Conover, Wang, Jiou
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318719/
https://ncbi.nlm.nih.gov/pubmed/22232551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.311977
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