Impaired Transforming Growth Factor-β (TGF-β) Transcriptional Activity and Cell Proliferation Control of a Menin In-frame Deletion Mutant Associated with Multiple Endocrine Neoplasia Type 1 (MEN1)

Multiple endocrine neoplasia type 1 (MEN1) is characterized by tumors of the parathyroid, enteropancreas, and anterior pituitary. The MEN1 gene encodes the tumor suppressor menin of 610 amino acids that has multiple protein partners and activities. The particular pathways that, when lost, lead to tu...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Canaff, Lucie, Vanbellinghen, Jean-François, Kaji, Hiroshi, Goltzman, David, Hendy, Geoffrey N.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2012
Gaiak:
Molecular Bases of Disease
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318699/
https://ncbi.nlm.nih.gov/pubmed/22275377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.341958
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