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The Immune Response to a Vesicular Stomatitis Virus Vaccine Vector Is Independent of Particulate Antigen Secretion and Protein Turnover Rate

Vesicular stomatitis virus (VSV) is a highly cytopathic virus being developed as a vaccine vector due to its ability to induce strong protective T cell and antibody responses after a single dose. However, little is known regarding the mechanisms underlying the potent immune responses elicited by VSV...

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Detalhes bibliográficos
Main Authors: Cobleigh, Melissa A., Bradfield, Clinton, Liu, Yuanjie, Mehta, Anand, Robek, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318607/
https://ncbi.nlm.nih.gov/pubmed/22345454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05991-11
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