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Residue Y161 of Influenza Virus Hemagglutinin Is Involved in Viral Recognition of Sialylated Complexes from Different Hosts

Influenza A virus glycoprotein hemagglutinin (HA) binds to host cell surface sialic acid (SA)-terminated sugars in glycoproteins to initiate viral entry. It is thought that avian influenza viruses preferentially bind to N-acetylneuraminic acid α3 (NeuAcα3) sugars, while human influenza viruses exhib...

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Hlavní autoři: Wang, Minxiu, Tscherne, Donna M., McCullough, Christopher, Caffrey, Michael, García-Sastre, Adolfo, Rong, Lijun
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318606/
https://ncbi.nlm.nih.gov/pubmed/22301136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.07187-11
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