The RalB Small GTPase Mediates Formation of Invadopodia through a GTPase-Activating Protein-Independent Function of the RalBP1/RLIP76 Effector

Our recent studies implicated key and distinct roles for the highly related RalA and RalB small GTPases (82% sequence identity) in pancreatic ductal adenocarcinoma (PDAC) tumorigenesis and invasive and metastatic growth, respectively. How RalB may promote PDAC invasion and metastasis has not been de...

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Bibliographic Details
Main Authors: Neel, Nicole F., Rossman, Kent L., Martin, Timothy D., Hayes, Tikvah K., Yeh, Jen Jen, Der, Channing J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318593/
https://ncbi.nlm.nih.gov/pubmed/22331470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06291-11
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