MacroH2A1 Regulates the Balance between Self-Renewal and Differentiation Commitment in Embryonic and Adult Stem Cells

One of the most striking epigenetic alterations that occurs at the level of the nucleosome is the complete exchange of the canonical H2A histones for the macroH2A variant. Here, we provide insight into the poorly recognized function of macroH2A in transcriptional activation and demonstrate its relev...

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Detalhes bibliográficos
Main Authors: Creppe, Catherine, Janich, Peggy, Cantariño, Neus, Noguera, Marc, Valero, Vanesa, Musulén, Eva, Douet, Julien, Posavec, Melanija, Martín-Caballero, Juan, Sumoy, Lauro, Di Croce, Luciano, Benitah, Salvador A., Buschbeck, Marcus
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318583/
https://ncbi.nlm.nih.gov/pubmed/22331466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06323-11
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