Performance Assessment of a Novel Two-Step Multiple Displacement Amplification-PCR Assay for Detection of Mycobacterium tuberculosis Complex in Sputum Specimens

A novel two-step multiple displacement amplification-PCR (MDA-PCR) assay for tuberculosis detection in 200 sputum specimens was evaluated. The MDA-PCR assay indicated a significant increase in sensitivity and specificity compared with those of standard PCR alone.

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Bibliographische Detailangaben
Hauptverfasser: Wu, Na, Zhang, Yuanyuan, Fu, Jun, Zhang, Ruifen, Feng, Lan, Hu, Yongfei, Li, Xiaoliang, Lu, Na, Zhao, Xiuqin, Pan, Yuanlong, Li, Jing, Zhu, Baoli, Wan, KangLin
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2012
Schlagworte:
Mycobacteriology and Aerobic Actinomycetes
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318506/
https://ncbi.nlm.nih.gov/pubmed/22259205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.05787-11
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