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Heterogeneity in Pseudomonas aeruginosa Biofilms Includes Expression of Ribosome Hibernation Factors in the Antibiotic-Tolerant Subpopulation and Hypoxia-Induced Stress Response in the Metabolically Active Population

Bacteria growing in biofilms are physiologically heterogeneous, due in part to their adaptation to local environmental conditions. Here, we characterized the local transcriptome responses of Pseudomonas aeruginosa growing in biofilms by using a microarray analysis of isolated biofilm subpopulations....

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Bibliografski detalji
Glavni autori: Williamson, Kerry S., Richards, Lee A., Perez-Osorio, Ailyn C., Pitts, Betsey, McInnerney, Kathleen, Stewart, Philip S., Franklin, Michael J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2012
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318454/
https://ncbi.nlm.nih.gov/pubmed/22343293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00022-12
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