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Molecular Characterizations of Cytolethal Distending Toxin Produced by Providencia alcalifaciens Strains Isolated from Patients with Diarrhea

Cytolethal distending toxins (CDTs), which block eukaryotic cell proliferation by acting as inhibitory cyclomodulins, are produced by diverse groups of Gram-negative bacteria. Active CDT is composed of three polypeptides—CdtA, CdtB, and CdtC—encoded by the genes cdtA, cdtB, and cdtC, respectively. W...

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Detalhes bibliográficos
Main Authors: Shima, Ayaka, Hinenoya, Atsushi, Asakura, Masahiro, Sugimoto, Norihiko, Tsukamoto, Teizo, Ito, Hideaki, Nagita, Akira, Faruque, Shah M., Yamasaki, Shinji
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318424/
https://ncbi.nlm.nih.gov/pubmed/22252871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05831-11
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