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In Vitro Potency and In Vivo Efficacy of a Novel Bis-Indole Antimicrobial Compound in Reducing Catheter Colonization

Vascular catheters coated with a novel antimicrobial agent (MBX1631) were studied for their ability to protect against bacterial colonization in vitro and in a rabbit model. MBX1631-coated catheters were significantly less likely to become colonized than control catheters both in vitro and in vivo (...

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Detalhes bibliográficos
Main Authors: Mansouri, Mohammad D., Opperman, Timothy J., Williams, John D., Stager, Charles, Darouiche, Rabih O.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318368/
https://ncbi.nlm.nih.gov/pubmed/22271864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05521-11
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