Expression of OXA-Type and SFO-1 β-Lactamases Induces Changes in Peptidoglycan Composition and Affects Bacterial Fitness

β-Lactamases and penicillin-binding proteins (PBPs) have evolved from a common ancestor. β-Lactamases are enzymes that degrade β-lactam antibiotics, whereas PBPs are involved in the synthesis and processing of peptidoglycan, which forms an elastic network in the bacterial cell wall. This study analy...

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Bibliographic Details
Main Authors: Fernández, Ana, Pérez, Astrid, Ayala, Juan A., Mallo, Susana, Rumbo-Feal, Soraya, Tomás, Maria, Poza, Margarita, Bou, Germán
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318342/
https://ncbi.nlm.nih.gov/pubmed/22290977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05402-11
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