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Xenoepitope Substitution Avoids Deceptive Imprinting and Broadens the Immune Response to Foot-and-Mouth Disease Virus

Many RNA viruses encode error-prone polymerases which introduce mutations into B and T cell epitopes, providing a mechanism for immunological escape. When regions of hypervariability are found within immunodominant epitopes with no known function, they are referred to as “decoy epitopes,” which ofte...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Szczepanek, Steven M., Barrette, Roger W., Rood, Debra, Alejo, Diana, Silbart, Lawrence K.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2012
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318270/
https://ncbi.nlm.nih.gov/pubmed/22323558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00035-12
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