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Nicotinamide, NAD(P)(H), and Methyl-Group Homeostasis Evolved and Became a Determinant of Ageing Diseases: Hypotheses and Lessons from Pellagra

Compartmentalized redox faults are common to ageing diseases. Dietary constituents are catabolized to NAD(H) donating electrons producing proton-based bioenergy in coevolved, cross-species and cross-organ networks. Nicotinamide and NAD deficiency from poor diet or high expenditure causes pellagra, a...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Williams, Adrian C., Hill, Lisa J., Ramsden, David B.
פורמט: Artigo
שפה:Inglês
יצא לאור: Hindawi Publishing Corporation 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318212/
https://ncbi.nlm.nih.gov/pubmed/22536229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/302875
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