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Mitochondria Death/Survival Signaling Pathways in Cardiotoxicity Induced by Anthracyclines and Anticancer-Targeted Therapies

Anthracyclines remain the cornerstone of treatment in many malignancies but these agents have a cumulative dose relationship with cardiotoxicity. Development of cardiomyopathy and congestive heart failure induced by anthracyclines are typically dose-dependent, irreversible, and cumulative. Although...

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Bibliografiske detaljer
Main Authors: Montaigne, David, Hurt, Christopher, Neviere, Remi
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318211/
https://ncbi.nlm.nih.gov/pubmed/22482055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/951539
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