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PlGF knockout delays brain vessel growth and maturation upon systemic hypoxic challenge
In this study, we have investigated the potential role of placental growth factor (PlGF) in hypoxia-induced brain angiogenesis. To this end, PlGF wild-type (PlGF(+/+)) and PlGF knockout (PlGF(−/−)) mice were exposed to whole body hypoxia (10% oxygen) for 7, 14, and 21 days. PlGF(+/+) animals exhibit...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3318143/ https://ncbi.nlm.nih.gov/pubmed/22126916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2011.167 |
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