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Fidelity of human immunodeficiency virus type I reverse transcriptase in copying natural DNA.

Reverse transcriptase from the human immunodeficiency virus type I (HIV-1) was expressed in E. coli and purified to near homogeneity. The enzyme was shown to contain reverse transcriptase, DNA polymerase and ribonuclease H activities. The DNA polymerase activity converted singly-primed phi X174 (+)...

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Bibliografiske detaljer
Main Authors: Weber, J, Grosse, F
Format: Artigo
Sprog:Inglês
Udgivet: 1989
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC331810/
https://ncbi.nlm.nih.gov/pubmed/2466238
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