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Thrombospondin-1 Type 1 Repeats in a Model of Inflammatory Bowel Disease: Transcript Profile and Therapeutic Effects

Thrombospondin-1 (TSP-1) is a matricellular protein with regulatory functions in inflammation and cancer. The type 1 repeats (TSR) domains of TSP-1 have been shown to interact with a wide range of proteins that result in the anti-angiogenic and anti-tumor properties of TSP-1. To ascertain possible f...

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Bibliografiske detaljer
Main Authors: Lopez-Dee, Zenaida P., Chittur, Sridar V., Patel, Bhumi, Stanton, Rebecca, Wakeley, Michelle, Lippert, Brittany, Menaker, Anastasya, Eiche, Bethany, Terry, Robert, Gutierrez, Linda S.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318003/
https://ncbi.nlm.nih.gov/pubmed/22509329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034590
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