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Turning gene function ON and OFF using sense and antisense photo-morpholinos in zebrafish

To understand the molecular mechanisms of development it is essential to be able to turn genes on and off at will and in a spatially restricted fashion. Morpholino oligonucleotides (MOs) are very common tools used in several model organisms with which it is possible to block gene expression. Recentl...

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Hlavní autoři: Tallafuss, Alexandra, Gibson, Dan, Morcos, Paul, Li, Yongfu, Seredick, Steve, Eisen, Judith, Washbourne, Philip
Médium: Artigo
Jazyk:Inglês
Vydáno: Company of Biologists 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317972/
https://ncbi.nlm.nih.gov/pubmed/22492359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.072702
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