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Loss of Llgl1 in retinal neuroepithelia reveals links between apical domain size, Notch activity and neurogenesis

To gain insights into the cellular mechanisms of neurogenesis, we analyzed retinal neuroepithelia deficient for Llgl1, a protein implicated in apicobasal cell polarity, asymmetric cell division, cell shape and cell cycle exit. We found that vertebrate retinal neuroepithelia deficient for Llgl1 retai...

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Main Authors: Clark, Brian S., Cui, Shuang, Miesfeld, Joel B., Klezovitch, Olga, Vasioukhin, Valeri, Link, Brian A.
Format: Artigo
Jezik:Inglês
Izdano: Company of Biologists 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317966/
https://ncbi.nlm.nih.gov/pubmed/22492354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.078097
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