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Mei-P26 regulates the maintenance of ovarian germline stem cells by promoting BMP signaling

In the Drosophila ovary, bone morphogenetic protein (BMP) ligands maintain germline stem cells (GSCs) in an undifferentiated state. The activation of the BMP pathway within GSCs results in the transcriptional repression of the differentiation factor bag of marbles (bam). The Nanos-Pumilio translatio...

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Hlavní autoři: Li, Yun, Maines, Jean Z., Tastan, Ömür Y., McKearin, Dennis M., Buszczak, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: Company of Biologists 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317963/
https://ncbi.nlm.nih.gov/pubmed/22438571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.077412
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