Multi-Level Interactions between the Nuclear Receptor TRα1 and the WNT Effectors β-Catenin/Tcf4 in the Intestinal Epithelium

Intestinal homeostasis results from complex cross-regulation of signaling pathways; their alteration induces intestinal tumorigenesis. Previously, we found that the thyroid hormone nuclear receptor TRα1 activates and synergizes with the WNT pathway, inducing crypt cell proliferation and promoting tu...

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Autores principales: Sirakov, Maria, Skah, Seham, Lone, Imtiaz Nisar, Nadjar, Julien, Angelov, Dimitar, Plateroti, Michelina
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317923/
https://ncbi.nlm.nih.gov/pubmed/22509275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034162
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