IL-4 determines eicosanoid formation in dendritic cells by down-regulation of 5-lipoxygenase and up-regulation of 15-lipoxygenase 1 expression

Dendritic cell (DC) differentiation from human CD34(+) hematopoietic progenitor cells (HPCs) can be triggered in vitro by a combination of cytokines consisting of stem cell factor, granulocyte-macrophage colony-stimulating factor, and tumor necrosis factor α. The immune response regulatory cytokines...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Spanbroek, Rainer, Hildner, Markus, Köhler, André, Müller, Angelika, Zintl, Felix, Kühn, Hartmut, Rådmark, Olof, Samuelsson, Bengt, Habenicht, Andreas J. R.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2001
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC33179/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11320251/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.091076998
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