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IL-4 determines eicosanoid formation in dendritic cells by down-regulation of 5-lipoxygenase and up-regulation of 15-lipoxygenase 1 expression

Dendritic cell (DC) differentiation from human CD34(+) hematopoietic progenitor cells (HPCs) can be triggered in vitro by a combination of cytokines consisting of stem cell factor, granulocyte-macrophage colony-stimulating factor, and tumor necrosis factor α. The immune response regulatory cytokines...

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Библиографические подробности
Главные авторы: Spanbroek, Rainer, Hildner, Markus, Köhler, André, Müller, Angelika, Zintl, Felix, Kühn, Hartmut, Rådmark, Olof, Samuelsson, Bengt, Habenicht, Andreas J. R.
Формат: Artigo
Язык:Inglês
Опубликовано: The National Academy of Sciences 2001
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC33179/
https://ncbi.nlm.nih.gov/pubmed/11320251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.091076998
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