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Use of the MLPA Assay in the Molecular Diagnosis of Gene Copy Number Alterations in Human Genetic Diseases

Multiplex Ligation-dependent Probe Amplification (MLPA) assay is a recently developed technique able to evidence variations in the copy number of several human genes. Due to this ability, MLPA can be used in the molecular diagnosis of several genetic diseases whose pathogenesis is related to the pre...

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Main Authors: Stuppia, Liborio, Antonucci, Ivana, Palka, Giandomenico, Gatta, Valentina
格式: Artigo
語言:Inglês
出版: Molecular Diversity Preservation International (MDPI) 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317712/
https://ncbi.nlm.nih.gov/pubmed/22489151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms13033245
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