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Phage Display Approaches for the Isolation of Monoclonal Antibodies Against Dengue Virus Envelope Domain III from Human and Mouse Derived Libraries

Domain III of the dengue virus envelope protein (EDIII, aa295-395) has an immunoglobulin fold and is the proposed receptor-binding domain of the virus. Previous studies have shown that monoclonal antibodies against EDIII can be neutralizing and have therapeutic potential. Here, cloned Fab-phage libr...

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Autors principals: Moreland, Nicole J., Susanto, Patricia, Lim, Elfin, Tay, Moon Y. F., Rajamanonmani, Ravikumar, Hanson, Brendon J., Vasudevan, Subhash G.
Format: Artigo
Idioma:Inglês
Publicat: Molecular Diversity Preservation International (MDPI) 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317677/
https://ncbi.nlm.nih.gov/pubmed/22489114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms13032618
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