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Differing and isoform-specific roles for the formin DIAPH3 in plasma membrane blebbing and filopodia formation
Plasma membrane (PM) blebs are dynamic actin-rich cell protrusions that occur, e.g., during cytokinesis, amoeboid cell motility and cell attachment. Using a targeted siRNA screen against 21 actin nucleation factors, we identify a novel and essential role of the human diaphanous formin DIAPH3 in PM b...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3317560/ https://ncbi.nlm.nih.gov/pubmed/22184005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2011.202 |
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