Myeloid Suppressor Cells Induced by Retinal Pigment Epithelial Cells Inhibit Autoreactive T-Cell Responses That Lead to Experimental Autoimmune Uveitis

PURPOSE. To test whether retinal pigment epithelial (RPE) cells are able to induce myeloid-derived suppressor cell (MDSC) differentiation from bone marrow (BM) progenitors. METHODS. BM cells were cocultured with or without RPE cells in the presence of GM-CSF and IL-4. Numbers of resultant MDSCs were...

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Main Authors: Tu, Zhidan, Li, Yan, Smith, Dawn, Doller, Catherine, Sugita, Sunao, Chan, Chi-Chao, Qian, Shiguang, Fung, John, Caspi, Rachel R., Lu, Lina, Lin, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: Association for Research in Vision and Ophthalmology, Inc. 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317433/
https://ncbi.nlm.nih.gov/pubmed/22247470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-8377
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