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Substratum Stiffness and Latrunculin B Regulate Matrix Gene and Protein Expression in Human Trabecular Meshwork Cells

PURPOSE. To determine the impact of substratum stiffness and latrunculin-B (Lat-B), on the expression of several matrix proteins that are associated with glaucoma. METHODS. Human trabecular meshwork (HTM) cells were cultured on hydrogels possessing stiffness values mimicking those found in normal (5...

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Main Authors: Thomasy, Sara M., Wood, Joshua A., Kass, Philip H., Murphy, Christopher J., Russell, Paul
Formato: Artigo
Idioma:Inglês
Publicado: Association for Research in Vision and Ophthalmology, Inc. 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317432/
https://ncbi.nlm.nih.gov/pubmed/22247475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-8526
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