Functional wiring of the yeast kinome revealed by global analysis of genetic network motifs

A combinatorial genetic perturbation strategy was applied to interrogate the yeast kinome on a genome-wide scale. We assessed the global effects of gene overexpression or gene deletion to map an integrated genetic interaction network of synthetic dosage lethal (SDL) and loss-of-function genetic inte...

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Detaylı Bibliyografya
Asıl Yazarlar: Sharifpoor, Sara, van Dyk, Dewald, Costanzo, Michael, Baryshnikova, Anastasia, Friesen, Helena, Douglas, Alison C., Youn, Ji-Young, VanderSluis, Benjamin, Myers, Chad L., Papp, Balázs, Boone, Charles, Andrews, Brenda J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2012
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Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317160/
https://ncbi.nlm.nih.gov/pubmed/22282571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.129213.111
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