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GRP78 Protein Expression in Ovarian Cancer Patients and Perspectives for a Drug-Targeting Approach

Glucose-regulated protein of 78 kD (GRP78) is a chaperone protein mainly located in the endoplasmic reticulum (ER). This protein is normally present at low levels in adult cells but its expression is triggered by ER stress including glucose deprivation and hypoxia. In tumor cells, it is overexpresse...

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Bibliografiske detaljer
Main Authors: Delie, Florence, Petignat, Patrick, Cohen, Marie
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317113/
https://ncbi.nlm.nih.gov/pubmed/22481929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/468615
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