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Alternating d(G-C)3 and d(C-G)3 hexanucleotides containing 7-deaza-2'-deoxyguanosine or 8-aza-7-deaza-2'-deoxyguanosine in place of dG.

The synthesis of alternating hexamers (8-13) derived from d(C-G)3 or d(G-C)3 but containing c7z8Gd (2) or c7Gd (3) instead of dG is described employing phosphoramidite-chemistry. Apart from the isobutyryl group the dimethylaminomethylene residue was used for the nucleobase-protection of 3. The methy...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Principais autores: Seela, F, Driller, H
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 1989
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC331711/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2922275/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/17.3.901
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