Efficient Nonviral Gene Therapy Using Folate-Targeted Chitosan-DNA Nanoparticles In Vitro

Nonviral cationic polymers like chitosan can be combined with DNA to protect it from degradation. The chitosan is a biocompatible, biodegradable, nontoxic, and cheap polycationic polymer with low immunogenicity. The objective of this study was to synthesize and then assess different chitosan-DNA nan...

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Autors principals: Jreyssaty, Christian, Shi, Qin, Wang, Huijie, Qiu, Xingping, Winnik, Françoise M., Zhang, Xiaoling, Dai, Kerong, Benderdour, Mohamed, Fernandes, Julio C.
Format: Artigo
Idioma:Inglês
Publicat: International Scholarly Research Network 2012
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317051/
https://ncbi.nlm.nih.gov/pubmed/22474605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5402/2012/369270
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