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Apolipoprotein E genotype affects tissue metallothionein levels: studies in targeted gene replacement mice

The apolipoprotein E (APOE) genotype is an important risk factor for ageing and age-related diseases. The APOE4 genotype (in contrast to APOE3) has been shown to be associated with oxidative stress and chronic inflammation. Metallothioneins (MT) exhibit antioxidant and anti-inflammatory activity, an...

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Detalhes bibliográficos
Main Authors: Graeser, Anne-Christin, Huebbe, Patricia, Storm, Niels, Höppner, Wolfgang, Döring, Frank, Wagner, Anika E., Rimbach, Gerald
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3316750/
https://ncbi.nlm.nih.gov/pubmed/22328270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12263-012-0282-x
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