Caesalpinia sappan extract inhibits IL1β-mediated overexpression of matrix metalloproteinases in human chondrocytes

Exacerbated production of matrix metalloproteinases (MMPs) is a key event in the progression of osteoarthritis (OA) and represents a promising target for the management of OA with nutraceuticals. In this study, we sought to determine the MMP-inhibitory activity of an ethanolic Caesalpinia sappan ext...

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Detalhes bibliográficos
Main Authors: Toegel, Stefan, Wu, Shengqian Q., Otero, Miguel, Goldring, Mary B., Leelapornpisid, Pimporn, Chiari, Catharina, Kolb, Alexander, Unger, Frank M., Windhager, Reinhard, Viernstein, Helmut
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2011
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3316743/
https://ncbi.nlm.nih.gov/pubmed/21850498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12263-011-0244-8
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