Astrocytic α(V)β(3) Integrin Inhibits Neurite Outgrowth and Promotes Retraction of Neuronal Processes by Clustering Thy-1

Thy-1 is a membrane glycoprotein suggested to stabilize or inhibit growth of neuronal processes. However, its precise function has remained obscure, because its endogenous ligand is unknown. We previously showed that Thy-1 binds directly to α(V)β(3) integrin in trans eliciting responses in astrocyte...

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Detalhes bibliográficos
Main Authors: Herrera-Molina, Rodrigo, Frischknecht, Renato, Maldonado, Horacio, Seidenbecher, Constanze I., Gundelfinger, Eckart D., Hetz, Claudio, Aylwin, María de la Luz, Schneider, Pascal, Quest, Andrew F. G., Leyton, Lisette
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3316703/
https://ncbi.nlm.nih.gov/pubmed/22479590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034295
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