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Tissue Architecture in the Caenorhabditis elegans Gonad Depends on Interactions Among Fibulin-1, Type IV Collagen and the ADAMTS Extracellular Protease

Molecules in the extracellular matrix (ECM) regulate cellular behavior in both development and pathology. Fibulin-1 is a conserved ECM protein. The Caenorhabditis elegans ortholog, FBL-1, regulates gonad-arm elongation and expansion by acting antagonistically to GON-1, an ADAMTS (a disintegrin and m...

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Autori principali: Kubota, Yukihiko, Nagata, Kayo, Sugimoto, Asako, Nishiwaki, Kiyoji
Natura: Artigo
Lingua:Inglês
Pubblicazione: Genetics Society of America 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3316650/
https://ncbi.nlm.nih.gov/pubmed/22298704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.111.133173
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