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A Knockout of the Tsg101 Gene Leads to Decreased Expression of ErbB Receptor Tyrosine Kinases and Induction of Autophagy Prior to Cell Death

The Tumor Susceptibility Gene 101 (Tsg101) encodes a multi-domain protein that mediates a variety of molecular and biological processes including the trafficking and lysosomal degradation of cell surface receptors. Conventional and conditional knockout models have demonstrated an essential requireme...

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Bibliografski detalji
Glavni autori: Morris, Chantey R., Stanton, Marissa J., Manthey, Karoline C., Oh, Keon Bong, Wagner, Kay-Uwe
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3316634/
https://ncbi.nlm.nih.gov/pubmed/22479596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034308
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