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EGF-Induced EMT and Invasiveness in Serous Borderline Ovarian Tumor Cells: A Possible Step in the Transition to Low-Grade Serous Carcinoma Cells?

In high-grade ovarian cancer cultures, it has been shown that epidermal growth factor (EGF) induces cell invasion by activating an epithelial-mesenchymal transition (EMT). However, the effect of EGF on serous borderline ovarian tumors (SBOT) and low-grade serous carcinomas (LGC) cell invasion remain...

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Detalhes bibliográficos
Main Authors: Cheng, Jung-Chien, Auersperg, Nelly, Leung, Peter C. K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3316602/
https://ncbi.nlm.nih.gov/pubmed/22479527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034071
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