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Knock-Down of Core Proteins Regulating MicroRNA Biogenesis Has No Effect on Sensitivity of Lung Cancer Cells to Ionizing Radiation

Recent studies underline the important role of microRNAs (miRNA) in the development of lung cancer. The main regulators of miRNA biogenesis are the ribonucleases Drosha, Dicer and Ago2. Here the role of core proteins of miRNA biogenesis machinery in the response of human non-small and small cell lun...

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Détails bibliographiques
Auteurs principaux: Surova, Olga, Akbar, Nadeem Shahzad, Zhivotovsky, Boris
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3316564/
https://ncbi.nlm.nih.gov/pubmed/22479364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033134
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