Chromatin Composition Is Changed by Poly(ADP-ribosyl)ation during Chromatin Immunoprecipitation

Chromatin-immunoprecipitation (ChIP) employs generally a mild formaldehyde cross-linking step, which is followed by isolation of specific protein-DNA complexes and subsequent PCR testing, to analyze DNA-protein interactions. Poly(ADP-ribosyl)ation, a posttranslational modification involved in divers...

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Main Authors: Beneke, Sascha, Meyer, Kirstin, Holtz, Anja, Hüttner, Katharina, Bürkle, Alexander
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3316553/
https://ncbi.nlm.nih.gov/pubmed/22479348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032914
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