Thymidylate synthase gene expression is stimulated by some (but not all) introns.
We previously described the construction of an intronless mouse thymidylate synthase (TS) minigene that has the normal 5' and 3' flanking regions of the gene linked to full length TS cDNA. Transfection of the minigene into ts- hamster V79 cells led to low level expression of normal mouse TS mRNA and...
Guardat en:
| Publicat a: | Nucleic Acids Res |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
1989
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| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC331609/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2915925/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/17.2.645 |
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