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Phosphoinositide lipid phosphatase SHIP1 and PTEN coordinate to regulate cell migration and adhesion

The second messenger phosphatidylinositol(3,4,5)P(3) (PtdIns(3,4,5)P(3)) is formed by stimulation of various receptors, including G protein–coupled receptors and integrins. The lipid phosphatases PTEN and SHIP1 are critical in regulating the level of PtdIns(3,4,5)P(3) during chemotaxis. Observations...

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Bibliografski detalji
Glavni autori: Mondal, Subhanjan, Subramanian, Kulandayan K., Sakai, Jiro, Bajrami, Besnik, Luo, Hongbo R.
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Cell Biology 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315799/
https://ncbi.nlm.nih.gov/pubmed/22323291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-10-0889
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