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Polymorphism discovery and allele frequency estimation using high-throughput DNA sequencing of target-enriched pooled DNA samples

BACKGROUND: The central role of the somatotrophic axis in animal post-natal growth, development and fertility is well established. Therefore, the identification of genetic variants affecting quantitative traits within this axis is an attractive goal. However, large sample numbers are a pre-requisite...

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Main Authors: Mullen, Michael P, Creevey, Christopher J, Berry, Donagh P, McCabe, Matt S, Magee, David A, Howard, Dawn J, Killeen, Aideen P, Park, Stephen D, McGettigan, Paul A, Lucy, Matt C, MacHugh, David E, Waters, Sinead M
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315736/
https://ncbi.nlm.nih.gov/pubmed/22235840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-16
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