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Evolutionary and Biochemical Aspects of Chemical Stress Resistance in Saccharomyces cerevisiae

Large-scale chemical genetics screens (chemogenomics) in yeast have been widely used to find drug targets, understand the mechanism-of-action of compounds, and unravel the biochemistry of drug resistance. Chemogenomics is based on the comparison of growth of gene deletants in the presence and absenc...

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Autors principals: Venancio, Thiago Motta, Bellieny-Rabelo, Daniel, Aravind, L.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Research Foundation 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315702/
https://ncbi.nlm.nih.gov/pubmed/22479268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2012.00047
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