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High dimensional and high resolution pulse sequences for backbone resonance assignment of intrinsically disordered proteins

Four novel 5D (HACA(N)CONH, HNCOCACB, (HACA)CON(CA)CONH, (H)NCO(NCA)CONH), and one 6D ((H)NCO(N)CACONH) NMR pulse sequences are proposed. The new experiments employ non-uniform sampling that enables achieving high resolution in indirectly detected dimensions. The experiments facilitate resonance ass...

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Main Authors: Zawadzka-Kazimierczuk, Anna, Koźmiński, Wiktor, Šanderová, Hana, Krásný, Libor
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315646/
https://ncbi.nlm.nih.gov/pubmed/22350953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-012-9613-x
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