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High dimensional and high resolution pulse sequences for backbone resonance assignment of intrinsically disordered proteins

Four novel 5D (HACA(N)CONH, HNCOCACB, (HACA)CON(CA)CONH, (H)NCO(NCA)CONH), and one 6D ((H)NCO(N)CACONH) NMR pulse sequences are proposed. The new experiments employ non-uniform sampling that enables achieving high resolution in indirectly detected dimensions. The experiments facilitate resonance ass...

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Autori principali: Zawadzka-Kazimierczuk, Anna, Koźmiński, Wiktor, Šanderová, Hana, Krásný, Libor
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Netherlands 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315646/
https://ncbi.nlm.nih.gov/pubmed/22350953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-012-9613-x
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