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RUNX3 Regulates Intercellular Adhesion Molecule 3 (ICAM-3) Expression during Macrophage Differentiation and Monocyte Extravasation

The adhesion molecule ICAM-3 belongs to the immunoglobulin gene superfamily and functions as a ligand for the β2 integrins LFA-1, Mac-1 and α(d)β(2). The expression of ICAM-3 is restricted to cells of the hematopoietic lineage. We present evidences that the ICAM-3 gene promoter exhibits a leukocyte-...

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Autori principali: Estecha, Ana, Aguilera-Montilla, Noemí, Sánchez-Mateos, Paloma, Puig-Kröger, Amaya
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315569/
https://ncbi.nlm.nih.gov/pubmed/22479382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033313
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