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Highly Parallel Translation of DNA Sequences into Small Molecules
A large body of in vitro evolution work establishes the utility of biopolymer libraries comprising 10(10) to 10(15) distinct molecules for the discovery of nanomolar-affinity ligands to proteins.[1], [2], [3], [4], [5] Small-molecule libraries of comparable complexity will likely provide nanomolar-a...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2012
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3315553/ https://ncbi.nlm.nih.gov/pubmed/22479303 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028056 |
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